Stochastic modeling suggests that noise reduces differentiation efficiency by inducing a heterogeneous drug response in glioma differentiation therapy

BACKGROUND: Glioma differentiation therapy is a novel strategy that has been used to induce glioma cells to differentiate into glia-like cells. Although some advances in experimental methods for exploring the molecular mechanisms involved in differentiation therapy have been made, a model-based comp...

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Detalles Bibliográficos
Autores principales: Sun, Xiaoqiang, Zhang, Jiajun, Zhao, Qi, Chen, Xing, Zhu, Wenbo, Yan, Guangmei, Zhou, Tianshou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982223/
https://www.ncbi.nlm.nih.gov/pubmed/27515956
http://dx.doi.org/10.1186/s12918-016-0316-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982223/
https://www.ncbi.nlm.nih.gov/pubmed/27515956
http://dx.doi.org/10.1186/s12918-016-0316-x

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