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Substance P promotes the recovery of oxidative stress-damaged retinal pigmented epithelial cells by modulating Akt/GSK-3β signaling

PURPOSE: Senescence of the retina causes an accumulation of reactive oxygen species (ROS). Oxidative stress associated with ROS can damage RPE cells, leading to neovascularization and severe ocular disorders, including age-related macular degeneration (AMD). Thus, the early treatment of the damage c...

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Detalles Bibliográficos
Autores principales: Baek, Sang-Min, Yu, Seung-Young, Son, Youngsook, Hong, Hyun Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982481/
https://www.ncbi.nlm.nih.gov/pubmed/27582624