Cargando…

NAD(P)H:quinone oxidoreductase 1 inducer activity of some novel anilinoquinazoline derivatives

The Kelch-like ECH-associated protein 1 (Keap1)/nuclear factor erythroid 2-related factor 2 (Nrf2)/antioxidant response elements pathway enables cells to survive oxidative stress conditions through regulating the expression of cytoprotective enzymes such as NAD(P)H:quinone oxidoreductase 1 (NQO1). T...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghorab, Mostafa M, Alsaid, Mansour S, Higgins, Maureen, Dinkova-Kostova, Albena T, Shahat, Abdelaaty A, Elghazawy, Nehal H, Arafa, Reem K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982500/
https://www.ncbi.nlm.nih.gov/pubmed/27540279
http://dx.doi.org/10.2147/DDDT.S105423