Cargando…

NAD(P)H:quinone oxidoreductase 1 inducer activity of some novel anilinoquinazoline derivatives

The Kelch-like ECH-associated protein 1 (Keap1)/nuclear factor erythroid 2-related factor 2 (Nrf2)/antioxidant response elements pathway enables cells to survive oxidative stress conditions through regulating the expression of cytoprotective enzymes such as NAD(P)H:quinone oxidoreductase 1 (NQO1). T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ghorab, Mostafa M, Alsaid, Mansour S, Higgins, Maureen, Dinkova-Kostova, Albena T, Shahat, Abdelaaty A, Elghazawy, Nehal H, Arafa, Reem K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982500/ https://www.ncbi.nlm.nih.gov/pubmed/27540279 http://dx.doi.org/10.2147/DDDT.S105423

Ejemplares similares

Flavonolignan 2,3-dehydrosilydianin activates Nrf2 and upregulates NAD(P)H:quinone oxidoreductase 1 in Hepa1c1c7 cells
por: Roubalová, Lenka, et al.
Publicado: (2017)

Update of the NAD(P)H:quinone oxidoreductase (NQO) gene family
por: Vasiliou, Vasilis, et al.
Publicado: (2006)

Roles of NAD(P)H:quinone Oxidoreductase 1 in Diverse Diseases
por: Lee, Wang-Soo, et al.
Publicado: (2021)

Structural Insights into the NAD(P)H:Quinone Oxidoreductase from Phytophthora capsici
por: Yang, Cancan, et al.
Publicado: (2022)

Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations
por: den Braver-Sewradj, Shalenie P., et al.
Publicado: (2017)

NAD(P)H:Quinone Oxidoreductase 1 (NQO1) Localizes to the Mitotic Spindle in Human Cells
por: Siegel, David, et al.
Publicado: (2012)

The potential roles of NAD(P)H:quinone oxidoreductase 1 in the development of diabetic nephropathy and actin polymerization
por: Moon, Sung-Je, et al.
Publicado: (2020)

Aerobic Cytotoxicity of Aromatic N-Oxides: The Role of NAD(P)H:Quinone Oxidoreductase (NQO1)
por: Nemeikaitė-Čėnienė, Aušra, et al.
Publicado: (2020)

Biphasic Kinetic Behavior of E. coli WrbA, an FMN-Dependent NAD(P)H:Quinone Oxidoreductase
por: Kishko, Iryna, et al.
Publicado: (2012)

NAD(P)H:Quinone Oxidoreductase 1 (NQO1) P187S Polymorphism and Prostate Cancer Risk in Caucasians
por: Stoehr, Christine G., et al.
Publicado: (2012)

Collapse of the native structure caused by a single amino acid exchange in human NAD(P)H:quinone oxidoreductase
por: Lienhart, Wolf-Dieter, et al.
Publicado: (2014)

Curcumin stabilizes p53 by interaction with NAD(P)H:quinone oxidoreductase 1 in tumor-derived cell lines
por: Patiño-Morales, Carlos César, et al.
Publicado: (2019)

NAD(P)H:Quinone Oxidoreductase-1 Expression Sensitizes Malignant Melanoma Cells to the HSP90 Inhibitor 17-AAG
por: Kasai, Shuya, et al.
Publicado: (2016)

NAD(P)H:quinone oxidoreductase 1 reduces the mutagenicity of DNA caused by NADPH:P450 reductase-activated metabolites of benzo(a)pyrene quinones.
por: Joseph, P., et al.
Publicado: (1998)

Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue
por: Pacheco-Garcia, Juan Luis, et al.
Publicado: (2021)

A small molecule chaperone rescues the stability and activity of a cancer‐associated variant of NAD(P)H:quinone oxidoreductase 1 in vitro
por: Strandback, Emilia, et al.
Publicado: (2019)

Attenuation of NAD[P]H:quinone oxidoreductase 1 aggravates prostate cancer and tumor cell plasticity through enhanced TGFβ signaling
por: Thapa, Dinesh, et al.
Publicado: (2020)

Arylamino-nor-β-lapachone derivative-induced apoptosis in human prostate cancer cells: involvement of NAD(P)H:quinone oxidoreductase (NQO1)
por: Cavalcanti, Bruno C, et al.
Publicado: (2013)

FAD-deficient P187S mutation of NAD(P)H:quinone oxidoreductase 1 (NQO1*2) binds and accelerates β-amyloid aggregation
por: Panja, Sudipta, et al.
Publicado: (2022)

Docosahexaenoic Acid Induces Expression of Heme Oxygenase-1 and NAD(P)H:quinone Oxidoreductase through Activation of Nrf2 in Human Mammary Epithelial Cells
por: Bang, Hye-Yoon, et al.
Publicado: (2017)

NAD(P)H:quinone oxidoreductase 1 determines radiosensitivity of triple negative breast cancer cells and is controlled by long non-coding RNA NEAT1
por: Lin, Li-Ching, et al.
Publicado: (2020)

A highly selective fluorescent probe for human NAD(P)H:quinone oxidoreductase 1 (hNQO1) detection and imaging in living tumor cells
por: Zhu, Ya, et al.
Publicado: (2019)

Methylmercury (MeHg) transcriptionally regulates NAD(P)H:quinone oxidoreductase 1 (NQO1) in Hepa-1c1c7 cells
por: Alqahtani, Mohammed A., et al.
Publicado: (2023)

Methylseleninic acid induces NAD(P)H:quinone oxidoreductase-1 expression through activation of NF-E2-related factor 2 in Chang liver cells
por: Park, Jong-Min, et al.
Publicado: (2016)

Correction: A highly selective fluorescent probe for human NAD(P)H:quinone oxidoreductase 1 (hNQO1) detection and imaging in living tumor cells
por: Zhu, Ya, et al.
Publicado: (2019)

A polymorphism in NAD(P)H:quinone oxidoreductase (NQO1): relationship of a homozygous mutation at position 609 of the NQO1 cDNA to NQO1 activity.
por: Ross, D., et al.
Publicado: (1996)

NAD(P)H: Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 Polymorphisms in Papillary Thyroid Microcarcinoma: Correlation with Phenotype
por: Lee, Junguee, et al.
Publicado: (2013)

A novel strategy for NQO1 (NAD(P)H:quinone oxidoreductase, EC 1.6.99.2) mediated therapy of bladder cancer based on the pharmacological properties of EO9
por: Choudry, G A, et al.
Publicado: (2001)

Dihydroartemisinin inhibits the viability of cervical cancer cells by upregulating caveolin 1 and mitochondrial carrier homolog 2: Involvement of p53 activation and NAD(P)H:quinone oxidoreductase 1 downregulation
por: Zhang, Ting, et al.
Publicado: (2017)

Riboflavin compounds show NAD(P)H dependent quinone oxidoreductase-like quinone reducing activity
por: Nagase, Midori, et al.
Publicado: (2023)

Identification of NAD(P)H Quinone Oxidoreductase Activity in Azoreductases from P. aeruginosa: Azoreductases and NAD(P)H Quinone Oxidoreductases Belong to the Same FMN-Dependent Superfamily of Enzymes
por: Ryan, Ali, et al.
Publicado: (2014)

β-Lapachone, a substrate of NAD(P)H:quinone oxidoreductase, induces anti-inflammatory heme oxygenase-1 via AMP-activated protein kinase activation in RAW264.7 macrophages
por: Byun, Seung Jae, et al.
Publicado: (2013)

Radiomodulatory effect of a non-electrophilic NQO1 inducer identified in a screen of new 6, 8-diiodoquinazolin-4(3H)-ones carrying a sulfonamide moiety
por: Soliman, Aiten M., et al.
Publicado: (2020)

Characterization of a polymorphism in NAD(P)H: quinone oxidoreductase (DT-diaphorase).
por: Traver, R. D., et al.
Publicado: (1997)

Cancer Cell Sensitivity to Redox-Cycling Quinones is Influenced by NAD(P)H: Quinone Oxidoreductase 1 Polymorphism
por: Glorieux, Christophe, et al.
Publicado: (2019)

Ajoene, a Major Organosulfide Found in Crushed Garlic, Induces NAD(P)H:quinone Oxidoreductase Expression Through Nuclear Factor E2-related Factor-2 Activation in Human Breast Epithelial Cells
por: Cho, Seung-Ju, et al.
Publicado: (2019)

Is NAD(P)H quinone oxidoreductase 1 a tumor promoter or suppressor in gastric cancer?
por: Cao, Lei, et al.
Publicado: (2023)

Suppression of NAD(P)H-quinone oxidoreductase 1 enhanced the susceptibility of cholangiocarcinoma cells to chemotherapeutic agents
por: Zeekpudsa, Ponsilp, et al.
Publicado: (2014)

Metabolism and Tissue Distribution of Chelerythrine and Effects of Macleaya Cordata Extracts on Liver NAD(P)H Quinone Oxidoreductase
por: Huang, Chong-Yin, et al.
Publicado: (2021)

Loss of Nrf2 abrogates the protective effect of Keap1 downregulation in a preclinical model of cutaneous squamous cell carcinoma
por: Knatko, Elena V., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_7n5g6c9nsngnjftsc9c208fl29