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Prevalence of CYP2D6*2, CYP2D6*4, CYP2D6*10, and CYP3A5*3 in Thai breast cancer patients undergoing tamoxifen treatment

BACKGROUND: Tamoxifen (TAM) is used in breast cancer treatment, but interindividual variabilities in TAM-metabolizing enzymes exist and have been linked to single nucleotide polymorphisms in the respective encoding genes. The different alleles and genotypes of these genes have been presented for Cau...

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Detalles Bibliográficos
Autores principales: Charoenchokthavee, Wanaporn, Panomvana, Duangchit, Sriuranpong, Virote, Areepium, Nutthada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982506/
https://www.ncbi.nlm.nih.gov/pubmed/27540311
http://dx.doi.org/10.2147/BCTT.S105563