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Improved skin permeation of methotrexate via nanosized ultradeformable liposomes

The aim of this study is to investigate methotrexate-entrapped ultradeformable liposomes (MTX-UDLs) for potential transdermal application. MTX-UDLs were prepared by extrusion method with phosphatidylcholine as a bilayer matrix and sodium cholate or Tween 80 as an edge activator. The physicochemical...

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Detalles Bibliográficos
Autores principales: Zeb, Alam, Qureshi, Omer Salman, Kim, Hyung-Seo, Cha, Ji-Hye, Kim, Hoo-Seong, Kim, Jin-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982511/
https://www.ncbi.nlm.nih.gov/pubmed/27540293
http://dx.doi.org/10.2147/IJN.S109565