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MicroRNA-148b Acts as a Tumor Suppressor in Cervical Cancer by Inducing G1/S-Phase Cell Cycle Arrest and Apoptosis in a Caspase-3-Dependent Manner

BACKGROUND: The purpose of our study was to investigate the role of microRNA (miR)-148b in cervical cancer. MATERIAL/METHODS: The expression of miR-148b was determined in HPV-16-immortalized cervical epithelial cell line CRL-2614 cells and in cervical cancer cell line HeLa cells. The miR-148b mimics...

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Detalles Bibliográficos
Autores principales: Mou, Zongmei, Xu, Xiangting, Dong, Mei, Xu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982527/
https://www.ncbi.nlm.nih.gov/pubmed/27505047
http://dx.doi.org/10.12659/MSM.896862