The Drug Excipient Cyclodextrin Interacts With d-Luciferin and Interferes With Bioluminescence Imaging

Cyclodextrins are well-characterized, barrel-shaped molecules that can solubilize organic small molecules in aqueous solution via host–guest interactions. As such, cyclodextrins are used as excipients for experimental therapeutics in vivo. We observed unanticipated modifications to bioluminescence i...

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Detalles Bibliográficos
Autores principales: Kumar, Jeyan S., Miller Jenkins, Lisa M., Gottesman, Michael M., Hall, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982550/
https://www.ncbi.nlm.nih.gov/pubmed/27030398
http://dx.doi.org/10.1177/1536012115625225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982550/
https://www.ncbi.nlm.nih.gov/pubmed/27030398
http://dx.doi.org/10.1177/1536012115625225

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