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Induction of apoptosis by HBI‐8000 in adult T‐cell leukemia/lymphoma is associated with activation of Bim and NLRP3

Adult T‐cell leukemia/lymphoma (ATL) is an aggressive T‐cell malignancy caused by human T‐cell lymphotropic virus 1. Treatment options for acute ATL patients include chemotherapy, stem cell transplantation, and recently the anti‐chemokine (C‐C motif) receptor 4 antibody, although most patients still...

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Detalles Bibliográficos
Autores principales: Hasegawa, Hiroo, Bissonnette, Reid P., Gillings, Mireille, Sasaki, Daisuke, Taniguchi, Hiroaki, Kitanosono, Hideaki, Tsuruda, Kazuto, Kosai, Kousuke, Uno, Naoki, Morinaga, Yoshitomo, Imaizumi, Yoshitaka, Miyazaki, Yasushi, Yanagihara, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982578/
https://www.ncbi.nlm.nih.gov/pubmed/27193821
http://dx.doi.org/10.1111/cas.12971