New mouse model of acute adult T‐cell leukemia generated by transplantation of AKT, BCLxL, and HBZ‐transduced T cells

Adult T‐cell leukemia/lymphoma (ATL) develops in human T‐cell leukemia virus type 1 (HTLV‐1) carriers. Although the HTLV‐1‐encoded HBZ gene is critically involved, HBZ alone is insufficient and additional, cooperative “hits” are required for the development of ATL. Candidate cooperative hits are bei...

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Detalles Bibliográficos
Autores principales: Kasugai, Yumiko, Yoshida, Noriaki, Ohshima, Koichi, Matsuo, Keitaro, Seto, Masao, Tsuzuki, Shinobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982588/
https://www.ncbi.nlm.nih.gov/pubmed/27223899
http://dx.doi.org/10.1111/cas.12974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982588/
https://www.ncbi.nlm.nih.gov/pubmed/27223899
http://dx.doi.org/10.1111/cas.12974

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