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New mouse model of acute adult T‐cell leukemia generated by transplantation of AKT, BCLxL, and HBZ‐transduced T cells

Adult T‐cell leukemia/lymphoma (ATL) develops in human T‐cell leukemia virus type 1 (HTLV‐1) carriers. Although the HTLV‐1‐encoded HBZ gene is critically involved, HBZ alone is insufficient and additional, cooperative “hits” are required for the development of ATL. Candidate cooperative hits are bei...

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Detalles Bibliográficos
Autores principales:	Kasugai, Yumiko, Yoshida, Noriaki, Ohshima, Koichi, Matsuo, Keitaro, Seto, Masao, Tsuzuki, Shinobu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982588/ https://www.ncbi.nlm.nih.gov/pubmed/27223899 http://dx.doi.org/10.1111/cas.12974

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