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Construction of a disulfide‐stabilized diabody against fibroblast growth factor‐2 and the inhibition activity in targeting breast cancer

Fibroblast growth factor‐2 (FGF‐2) is one of the most important angiogenic factors to promote tumor growth, progression and metastasis. Neutralizing antibodies against FGF‐2 may suppress the growth of tumor cells by blocking the FGF‐2 signaling pathway. In this study, a disulfide‐stabilized diabody...

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Detalles Bibliográficos
Autores principales: Cai, Yaxiong, Zhang, Jinxia, Lao, Xuejun, Jiang, Haowu, Yu, Yunfei, Deng, Yanrui, Zhong, Jiangchuan, Liang, Yiye, Xiong, Likuan, Deng, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982589/
https://www.ncbi.nlm.nih.gov/pubmed/27251178
http://dx.doi.org/10.1111/cas.12981