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Construction of a disulfide‐stabilized diabody against fibroblast growth factor‐2 and the inhibition activity in targeting breast cancer
Fibroblast growth factor‐2 (FGF‐2) is one of the most important angiogenic factors to promote tumor growth, progression and metastasis. Neutralizing antibodies against FGF‐2 may suppress the growth of tumor cells by blocking the FGF‐2 signaling pathway. In this study, a disulfide‐stabilized diabody...
Autores principales: | Cai, Yaxiong, Zhang, Jinxia, Lao, Xuejun, Jiang, Haowu, Yu, Yunfei, Deng, Yanrui, Zhong, Jiangchuan, Liang, Yiye, Xiong, Likuan, Deng, Ning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982589/ https://www.ncbi.nlm.nih.gov/pubmed/27251178 http://dx.doi.org/10.1111/cas.12981 |
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