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Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems

BACKGROUND: Schistosomiasis, one of the world’s greatest human neglected tropical diseases, is caused by parasitic trematodes of the genus Schistosoma. A unique feature of schistosome biology is that the induction of sexual maturation as well as the maintenance of the differentiation status of femal...

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Detalles Bibliográficos
Autores principales: Guidi, Alessandra, Lalli, Cristiana, Perlas, Emerald, Bolasco, Giulia, Nibbio, Martina, Monteagudo, Edith, Bresciani, Alberto, Ruberti, Giovina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982595/
https://www.ncbi.nlm.nih.gov/pubmed/27518281
http://dx.doi.org/10.1371/journal.pntd.0004928