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Importin β Can Bind Hepatitis B Virus Core Protein and Empty Core-Like Particles and Induce Structural Changes

Hepatitis B virus (HBV) capsids are found in many forms: immature single-stranded RNA-filled cores, single-stranded DNA-filled replication intermediates, mature cores with relaxed circular double-stranded DNA, and empty capsids. A capsid, the protein shell of the core, is a complex of 240 copies of...

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Detalles Bibliográficos
Autores principales: Chen, Chao, Wang, Joseph Che-Yen, Pierson, Elizabeth E., Keifer, David Z., Delaleau, Mildred, Gallucci, Lara, Cazenave, Christian, Kann, Michael, Jarrold, Martin F., Zlotnick, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982637/
https://www.ncbi.nlm.nih.gov/pubmed/27518410
http://dx.doi.org/10.1371/journal.ppat.1005802