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Importin β Can Bind Hepatitis B Virus Core Protein and Empty Core-Like Particles and Induce Structural Changes
Hepatitis B virus (HBV) capsids are found in many forms: immature single-stranded RNA-filled cores, single-stranded DNA-filled replication intermediates, mature cores with relaxed circular double-stranded DNA, and empty capsids. A capsid, the protein shell of the core, is a complex of 240 copies of...
Autores principales: | Chen, Chao, Wang, Joseph Che-Yen, Pierson, Elizabeth E., Keifer, David Z., Delaleau, Mildred, Gallucci, Lara, Cazenave, Christian, Kann, Michael, Jarrold, Martin F., Zlotnick, Adam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982637/ https://www.ncbi.nlm.nih.gov/pubmed/27518410 http://dx.doi.org/10.1371/journal.ppat.1005802 |
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