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A Mechanistic Model for Cooperative Behavior of Co-transcribing RNA Polymerases

In fast-transcribing prokaryotic genes, such as an rrn gene in Escherichia coli, many RNA polymerases (RNAPs) transcribe the DNA simultaneously. Active elongation of RNAPs is often interrupted by pauses, which has been observed to cause RNAP traffic jams; yet some studies indicate that elongation se...

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Detalles Bibliográficos
Autores principales: Heberling, Tamra, Davis, Lisa, Gedeon, Jakub, Morgan, Charles, Gedeon, Tomáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982667/
https://www.ncbi.nlm.nih.gov/pubmed/27517607
http://dx.doi.org/10.1371/journal.pcbi.1005069