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Flavonoids as CDK1 Inhibitors: Insights in Their Binding Orientations and Structure-Activity Relationship
In the last years, the interactions of flavonoids with protein kinases (PKs) have been described by using crystallographic experiments. Interestingly, different orientations have been found for one flavonoid inside different PKs and different chemical substitutions lead to different orientations of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982677/ https://www.ncbi.nlm.nih.gov/pubmed/27517610 http://dx.doi.org/10.1371/journal.pone.0161111 |