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Defining the Product Chemical Space of Monoterpenoid Synthases

Terpenoid synthases create diverse carbon skeletons by catalyzing complex carbocation rearrangements, making them particularly challenging for enzyme function prediction. To begin to address this challenge, we have developed a computational approach for the systematic enumeration of terpenoid carboc...

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Detalles Bibliográficos
Autores principales: Tian, Boxue, Poulter, C. Dale, Jacobson, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982680/
https://www.ncbi.nlm.nih.gov/pubmed/27517297
http://dx.doi.org/10.1371/journal.pcbi.1005053