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HIRA Is Required for Heart Development and Directly Regulates Tnni2 and Tnnt3

Chromatin remodelling is essential for cardiac development. Interestingly, the role of histone chaperones has not been investigated in this regard. HIRA is a member of the HUCA (HIRA/UBN1/CABIN1/ASF1a) complex that deposits the variant histone H3.3 on chromatin independently of replication. Lack of...

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Detalles Bibliográficos
Autores principales: Dilg, Daniel, Saleh, Rasha Noureldin M., Phelps, Sarah Elizabeth Lee, Rose, Yoann, Dupays, Laurent, Murphy, Cian, Mohun, Timothy, Anderson, Robert H., Scambler, Peter J., Chapgier, Ariane L. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982693/
https://www.ncbi.nlm.nih.gov/pubmed/27518902
http://dx.doi.org/10.1371/journal.pone.0161096