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All Subdomains of the Talin Rod Are Mechanically Vulnerable and May Contribute To Cellular Mechanosensing

[Image: see text] Although the relevance of mechanotransduction in cell signaling is currently appreciated, the mechanisms that drive this process remain largely unknown. Mechanical unfolding of proteins may trigger distinct downstream signals in cells, providing a mechanism for cellular mechanotran...

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Detalles Bibliográficos
Autores principales: Haining, Alexander William M., von Essen, Magdaléna, Attwood, Simon J., Hytönen, Vesa P., del Río Hernández, Armando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982699/
https://www.ncbi.nlm.nih.gov/pubmed/27380548
http://dx.doi.org/10.1021/acsnano.6b01658