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Associations Between Common and Rare Exonic Genetic Variants and Serum Levels of 20 Cardiovascular-Related Proteins: The Tromsø Study

BACKGROUND—: Genetic variation can be used to study causal relationships between biomarkers and diseases. Here, we identify new common and rare genetic variants associated with cardiovascular-related protein levels (protein quantitative trait loci [pQTLs]). We functionally annotate these pQTLs, pred...

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Detalles Bibliográficos
Autores principales: Solomon, Terry, Smith, Erin N., Matsui, Hiroko, Braekkan, Sigrid K., Wilsgaard, Tom, Njølstad, Inger, Mathiesen, Ellisiv B., Hansen, John-Bjarne, Frazer, Kelly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982757/
https://www.ncbi.nlm.nih.gov/pubmed/27329291
http://dx.doi.org/10.1161/CIRCGENETICS.115.001327