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Associations Between Common and Rare Exonic Genetic Variants and Serum Levels of 20 Cardiovascular-Related Proteins: The Tromsø Study
BACKGROUND—: Genetic variation can be used to study causal relationships between biomarkers and diseases. Here, we identify new common and rare genetic variants associated with cardiovascular-related protein levels (protein quantitative trait loci [pQTLs]). We functionally annotate these pQTLs, pred...
Autores principales: | Solomon, Terry, Smith, Erin N., Matsui, Hiroko, Braekkan, Sigrid K., Wilsgaard, Tom, Njølstad, Inger, Mathiesen, Ellisiv B., Hansen, John-Bjarne, Frazer, Kelly A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982757/ https://www.ncbi.nlm.nih.gov/pubmed/27329291 http://dx.doi.org/10.1161/CIRCGENETICS.115.001327 |
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