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Genotype-Dependent Effects of Dalcetrapib on Cholesterol Efflux and Inflammation: Concordance With Clinical Outcomes

BACKGROUND—: Dalcetrapib effects on cardiovascular outcomes are determined by adenylate cyclase 9 gene polymorphisms. Our aim was to determine whether these clinical end point results are also associated with changes in reverse cholesterol transport and inflammation. METHODS AND RESULTS—: Participan...

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Detalles Bibliográficos
Autores principales: Tardif, Jean-Claude, Rhainds, David, Brodeur, Mathieu, Feroz Zada, Yassamin, Fouodjio, René, Provost, Sylvie, Boulé, Marie, Alem, Sonia, Grégoire, Jean C., L’Allier, Philippe L., Ibrahim, Reda, Guertin, Marie-Claude, Mongrain, Ian, Olsson, Anders G., Schwartz, Gregory G., Rhéaume, Eric, Dubé, Marie-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982759/
https://www.ncbi.nlm.nih.gov/pubmed/27418594
http://dx.doi.org/10.1161/CIRCGENETICS.116.001405