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Disruption of insulin receptor function inhibits proliferation in endocrine resistant breast cancer cells
The insulin-like growth factor (IGF) system is a well-studied growth regulatory pathway implicated in breast cancer biology. Clinical trials testing monoclonal antibodies directed against the type I IGF receptor (IGF1R) in combination with estrogen receptor-α (ER) targeting have been completed, but...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982805/ https://www.ncbi.nlm.nih.gov/pubmed/26876199 http://dx.doi.org/10.1038/onc.2015.488 |