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Development of Gonadotropin-Releasing Hormone-Secreting Neurons from Human Pluripotent Stem Cells

Gonadotropin-releasing hormone (GnRH) neurons regulate human puberty and reproduction. Modeling their development and function in vitro would be of interest for both basic research and clinical translation. Here, we report a three-step protocol to differentiate human pluripotent stem cells (hPSCs) i...

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Detalles Bibliográficos
Autores principales: Lund, Carina, Pulli, Kristiina, Yellapragada, Venkatram, Giacobini, Paolo, Lundin, Karolina, Vuoristo, Sanna, Tuuri, Timo, Noisa, Parinya, Raivio, Taneli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982984/
https://www.ncbi.nlm.nih.gov/pubmed/27426041
http://dx.doi.org/10.1016/j.stemcr.2016.06.007