Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency

Induced pluripotent stem cells (iPSCs) represent an innovative source for the standardized in vitro generation of macrophages (Mφ). We here describe a robust and efficient protocol to obtain mature and functional Mφ from healthy as well as disease-specific murine iPSCs. With regard to morphology, su...

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Detalles Bibliográficos
Autores principales: Mucci, Adele, Kunkiel, Jessica, Suzuki, Takuji, Brennig, Sebastian, Glage, Silke, Kühnel, Mark P., Ackermann, Mania, Happle, Christine, Kuhn, Alexandra, Schambach, Axel, Trapnell, Bruce C., Hansen, Gesine, Moritz, Thomas, Lachmann, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982988/
https://www.ncbi.nlm.nih.gov/pubmed/27453007
http://dx.doi.org/10.1016/j.stemcr.2016.06.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982988/
https://www.ncbi.nlm.nih.gov/pubmed/27453007
http://dx.doi.org/10.1016/j.stemcr.2016.06.011

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