Suppression of the inflammatory response by disease-inducible interleukin-10 gene therapy in a three-dimensional micromass model of the human synovial membrane

BACKGROUND: Gene therapy has the potential to provide long-term production of therapeutic proteins in the joints of osteoarthritis (OA) patients. The objective of this study was to analyse the therapeutic potential of disease-inducible expression of anti-inflammatory interleukin-10 (IL-10) in the th...

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Detalles Bibliográficos
Autores principales: Broeren, Mathijs G. A., de Vries, Marieke, Bennink, Miranda B., Arntz, Onno J., van Lent, Peter L. E M., van der Kraan, Peter M., van den Berg, Wim B., van den Hoogen, Frank H. J., Koenders, Marije I., van de Loo, Fons A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983024/
https://www.ncbi.nlm.nih.gov/pubmed/27519904
http://dx.doi.org/10.1186/s13075-016-1083-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983024/
https://www.ncbi.nlm.nih.gov/pubmed/27519904
http://dx.doi.org/10.1186/s13075-016-1083-1

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