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Early Endothelial Progenitor Cells (eEPCs) in systemic sclerosis (SSc) - dynamics of cellular regeneration and mesenchymal transdifferentiation

BACKGROUND: Patients with systemic sclerosis (SSc) are endagered by tissue fibrosis and by microvasculopathy, with the latter caused by endothelial cell expansion/proliferation. SSc-associated fibrosis potentially results from mesenchymal transdifferentiation of endothelial cells. Early Endothelial...

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Detalles Bibliográficos
Autores principales: Patschan, S., Tampe, D., Müller, C., Seitz, C., Herink, C., Müller, G. A., Zeisberg, E., Zeisberg, M., Henze, E., Patschan, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983068/
https://www.ncbi.nlm.nih.gov/pubmed/27519706
http://dx.doi.org/10.1186/s12891-016-1197-2