A new tool for tuberculosis vaccine screening: Ex vivo Mycobacterial Growth Inhibition Assay indicates BCG-mediated protection in a murine model of tuberculosis

BACKGROUND: In the absence of a validated animal model and/or an immune correlate which predict vaccine-mediated protection, large-scale clinical trials are currently the only option to prove efficacy of new tuberculosis candidate vaccines. Tools to facilitate testing of new tuberculosis (TB) vaccin...

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Detalles Bibliográficos
Autores principales: Zelmer, Andrea, Tanner, Rachel, Stylianou, Elena, Damelang, Timon, Morris, Sheldon, Izzo, Angelo, Williams, Ann, Sharpe, Sally, Pepponi, Ilaria, Walker, Barry, Hokey, David A., McShane, Helen, Brennan, Michael, Fletcher, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983071/
https://www.ncbi.nlm.nih.gov/pubmed/27519524
http://dx.doi.org/10.1186/s12879-016-1751-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983071/
https://www.ncbi.nlm.nih.gov/pubmed/27519524
http://dx.doi.org/10.1186/s12879-016-1751-4

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