SEC Based Method for Size Determination of Immune Complexes of Therapeutic Antibodies in Animal Matrix

Therapeutic monoclonal antibodies (mAbs) represent a milestone in pharmacological development. Their superiority is based on the combination of high specificity, low toxicity, and long half-life that characterizes biologics. If biologics have Achilles' heel, it is their potential immunogenicity...

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Detalles Bibliográficos
Autores principales: Boysen, Marta, Schlicksupp, Laura, Dreher, Ingeborg, Loebbert, Ralf, Richter, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983373/
https://www.ncbi.nlm.nih.gov/pubmed/27556050
http://dx.doi.org/10.1155/2016/9096059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983373/
https://www.ncbi.nlm.nih.gov/pubmed/27556050
http://dx.doi.org/10.1155/2016/9096059

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