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SEC Based Method for Size Determination of Immune Complexes of Therapeutic Antibodies in Animal Matrix
Therapeutic monoclonal antibodies (mAbs) represent a milestone in pharmacological development. Their superiority is based on the combination of high specificity, low toxicity, and long half-life that characterizes biologics. If biologics have Achilles' heel, it is their potential immunogenicity...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983373/ https://www.ncbi.nlm.nih.gov/pubmed/27556050 http://dx.doi.org/10.1155/2016/9096059 |