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Calcineurin β protects brain after injury by activating the unfolded protein response
The Ca(2+)-dependent phosphatase, calcineurin (CN) is thought to play a detrimental role in damaged neurons; however, its role in astrocytes is unclear. In cultured astrocytes, CNβ expression increased after treatment with a sarco/endoplasmic reticulum Ca(2+)-ATPase inhibitor, thapsigargin, and with...
Autores principales: | Chen, Yanan, Holstein, Deborah M., Aime, Sofia, Bollo, Mariana, Lechleiter, James D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983525/ https://www.ncbi.nlm.nih.gov/pubmed/27334877 http://dx.doi.org/10.1016/j.nbd.2016.06.011 |
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