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Flexible analysis of digital PCR experiments using generalized linear mixed models

The use of digital PCR for quantification of nucleic acids is rapidly growing. A major drawback remains the lack of flexible data analysis tools. Published analysis approaches are either tailored to specific problem settings or fail to take into account sources of variability. We propose the general...

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Detalles Bibliográficos
Autores principales: Vynck, Matthijs, Vandesompele, Jo, Nijs, Nele, Menten, Björn, De Ganck, Ariane, Thas, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983648/
https://www.ncbi.nlm.nih.gov/pubmed/27551671
http://dx.doi.org/10.1016/j.bdq.2016.06.001