Cargando…

Involvement of GABA(B) Receptor Signaling in Antipsychotic-like Action of the Novel Orthosteric Agonist of the mGlu(4) Receptor, LSP4-2022

Considering that ligands of metabotropic glutamate and GABA receptors may exert beneficial effects on schizophrenia, we assessed the actions of the first mGlu(4)-selective orthosteric agonist, LSP4-2022, in several tests reflecting positive, negative, and cognitive symptoms of schizophrenia. Moreove...

Descripción completa

Detalles Bibliográficos
Autores principales: Woźniak, Monika, Acher, Francine, Marciniak, Marcin, Łasoń-Tyburkiewicz, Magdalena, Gruca, Piotr, Papp, Mariusz, Pilc, Andrzej, Wierońska, Joanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983756/
https://www.ncbi.nlm.nih.gov/pubmed/26769224
http://dx.doi.org/10.2174/1570159X13666150516000630