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Involvement of GABA(B) Receptor Signaling in Antipsychotic-like Action of the Novel Orthosteric Agonist of the mGlu(4) Receptor, LSP4-2022
Considering that ligands of metabotropic glutamate and GABA receptors may exert beneficial effects on schizophrenia, we assessed the actions of the first mGlu(4)-selective orthosteric agonist, LSP4-2022, in several tests reflecting positive, negative, and cognitive symptoms of schizophrenia. Moreove...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983756/ https://www.ncbi.nlm.nih.gov/pubmed/26769224 http://dx.doi.org/10.2174/1570159X13666150516000630 |