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Involvement of GABA(B) Receptor Signaling in Antipsychotic-like Action of the Novel Orthosteric Agonist of the mGlu(4) Receptor, LSP4-2022

Considering that ligands of metabotropic glutamate and GABA receptors may exert beneficial effects on schizophrenia, we assessed the actions of the first mGlu(4)-selective orthosteric agonist, LSP4-2022, in several tests reflecting positive, negative, and cognitive symptoms of schizophrenia. Moreove...

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Detalles Bibliográficos
Autores principales:	Woźniak, Monika, Acher, Francine, Marciniak, Marcin, Łasoń-Tyburkiewicz, Magdalena, Gruca, Piotr, Papp, Mariusz, Pilc, Andrzej, Wierońska, Joanna M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983756/ https://www.ncbi.nlm.nih.gov/pubmed/26769224 http://dx.doi.org/10.2174/1570159X13666150516000630

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