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Group I mGluR Induced LTD of NMDAR-synaptic Transmission at the Schaffer Collateral but not Temperoammonic Input to CA1

NMDA receptors are composed of multiple subunits and are crucial in the induction of synaptic plasticity and learning and memory. In this study, application of the group I mGlu receptor agonist, DHPG, caused LTD of NMDA-EPSCs (DHPG-LTD(NMDA)) of the Schaffer collateral, but not of NMDA-EPSCs of the...

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Detalles Bibliográficos
Autores principales: Fitzjohn, Stephen, Bashir, Zafar, Farrow, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983758/
https://www.ncbi.nlm.nih.gov/pubmed/27296639
http://dx.doi.org/10.2174/1570159X13666150615221502