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Functional impact of splice isoform diversity in individual cells

Alternative pre-mRNA splicing provides an effective means for expanding coding capacity of eukaryotic genomes. Recent studies suggest that co-expression of different splice isoforms may increase diversity of RNAs and proteins at a single-cell level. A pertinent question in the field is whether such...

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Detalles Bibliográficos
Autores principales: Yap, Karen, Makeyev, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984447/
https://www.ncbi.nlm.nih.gov/pubmed/27528755
http://dx.doi.org/10.1042/BST20160103