Loss of N-acetylgalactosaminyltransferase 3 in poorly differentiated pancreatic cancer: augmented aggressiveness and aberrant ErbB family glycosylation

BACKGROUND: Aberrant glycosylation of several proteins underlie pancreatic ductal adenocarcinoma (PDAC) progression and metastasis. O-glycosylation is initiated by a family of enzymes known as polypeptide N-acetylgalactosaminyl transferases (GalNAc-Ts/GALNTs). In this study, we investigated the role...

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Detalles Bibliográficos
Autores principales: Chugh, Seema, Meza, Jane, Sheinin, Yuri M, Ponnusamy, Moorthy P, Batra, Surinder K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984453/
https://www.ncbi.nlm.nih.gov/pubmed/27187683
http://dx.doi.org/10.1038/bjc.2016.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984453/
https://www.ncbi.nlm.nih.gov/pubmed/27187683
http://dx.doi.org/10.1038/bjc.2016.116

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