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Loss of N-acetylgalactosaminyltransferase 3 in poorly differentiated pancreatic cancer: augmented aggressiveness and aberrant ErbB family glycosylation

BACKGROUND: Aberrant glycosylation of several proteins underlie pancreatic ductal adenocarcinoma (PDAC) progression and metastasis. O-glycosylation is initiated by a family of enzymes known as polypeptide N-acetylgalactosaminyl transferases (GalNAc-Ts/GALNTs). In this study, we investigated the role...

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Detalles Bibliográficos
Autores principales:	Chugh, Seema, Meza, Jane, Sheinin, Yuri M, Ponnusamy, Moorthy P, Batra, Surinder K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984453/ https://www.ncbi.nlm.nih.gov/pubmed/27187683 http://dx.doi.org/10.1038/bjc.2016.116

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