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Release of Infectious Hepatitis C Virus from Huh7 Cells Occurs via a trans-Golgi Network-to-Endosome Pathway Independent of Very-Low-Density Lipoprotein Secretion

The release of infectious hepatitis C virus (HCV) particles from infected cells remains poorly characterized. We previously demonstrated that virus release is dependent on the endosomal sorting complex required for transport (ESCRT). Here, we show a critical role of trans-Golgi network (TGN)-endosom...

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Detalles Bibliográficos
Autores principales: Mankouri, Jamel, Walter, Cheryl, Stewart, Hazel, Bentham, Matthew, Park, Wei Sun, Heo, Won Do, Fukuda, Mitsunori, Griffin, Stephen, Harris, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984645/
https://www.ncbi.nlm.nih.gov/pubmed/27226379
http://dx.doi.org/10.1128/JVI.00826-16