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The clinical implications of gene mutations in chronic lymphocytic leukaemia

Chronic lymphocytic leukaemia (CLL) is a molecularly heterogeneous disease as revealed by recent genomic studies. Among genetic lesions that are recurrent in CLL, few clinically validated prognostic markers, such as TP53 mutations and 17p deletion, are available for the use in clinical practice to g...

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Detalles Bibliográficos
Autores principales: Rossi, Davide, Gaidano, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984803/
https://www.ncbi.nlm.nih.gov/pubmed/27031852
http://dx.doi.org/10.1038/bjc.2016.78