Loss of the cell polarity determinant human Discs-large is a novel molecular marker of nodal involvement and poor prognosis in endometrial cancer

BACKGROUND: Recent Drosophila studies showed that Discs-large (Dlg) is critical for regulation of cell polarity and tissue architecture. We investigated the possibility that loss of the human homologue of Drosophila Dlg (DLG1) is involved in endometrial carcinogenesis. METHODS: We analysed DLG1 expr...

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Detalles Bibliográficos
Autores principales: Sugihara, Takeru, Nakagawa, Shunsuke, Sasajima, Yuko, Ichinose, Takayuki, Hiraike, Haruko, Kondo, Fukuo, Uozaki, Hiroshi, Fukusato, Toshio, Ayabe, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984904/
https://www.ncbi.nlm.nih.gov/pubmed/27002939
http://dx.doi.org/10.1038/bjc.2016.24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984904/
https://www.ncbi.nlm.nih.gov/pubmed/27002939
http://dx.doi.org/10.1038/bjc.2016.24

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