Design and characteristics of cytotoxic fibroblast growth factor 1 conjugate for fibroblast growth factor receptor-targeted cancer therapy

Fibroblast growth factor receptors (FGFRs) are attractive candidate cancer therapy targets as they are overexpressed in multiple types of tumors, such as breast, prostate, bladder, and lung cancer. In this study, a natural ligand of FGFR, an engineered variant of fibroblast growth factor 1 (FGF1(V))...

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Detalles Bibliográficos
Autores principales: Szlachcic, Anna, Zakrzewska, Malgorzata, Lobocki, Michal, Jakimowicz, Piotr, Otlewski, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984993/
https://www.ncbi.nlm.nih.gov/pubmed/27563235
http://dx.doi.org/10.2147/DDDT.S105896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984993/
https://www.ncbi.nlm.nih.gov/pubmed/27563235
http://dx.doi.org/10.2147/DDDT.S105896

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