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Generation of Functional RNAs from Inactive Oligonucleotide Complexes by Non-enzymatic Primer Extension
[Image: see text] The earliest genomic RNAs had to be short enough for efficient replication, while simultaneously serving as unfolded templates and effective ribozymes. A partial solution to this paradox may lie in the fact that many functional RNAs can self-assemble from multiple fragments. Theref...
Autores principales: | Adamala, Katarzyna, Engelhart, Aaron E., Szostak, Jack W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984999/ https://www.ncbi.nlm.nih.gov/pubmed/25521912 http://dx.doi.org/10.1021/ja511564d |
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