p62/Sequestosome-1 Is Indispensable for Maturation and Stabilization of Mallory-Denk Bodies

Mallory-Denk bodies (MDBs) are hepatocytic protein aggregates found in steatohepatitis and several other chronic liver diseases as well as hepatocellular carcinoma. MDBs are mainly composed of phosphorylated keratins and stress protein p62/Sequestosome-1 (p62), which is a common component of cytopla...

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Detalles Bibliográficos
Autores principales: Lahiri, Pooja, Schmidt, Volker, Smole, Claudia, Kufferath, Iris, Denk, Helmut, Strnad, Pavel, Rülicke, Thomas, Fröhlich, Leopold F., Zatloukal, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985067/
https://www.ncbi.nlm.nih.gov/pubmed/27526095
http://dx.doi.org/10.1371/journal.pone.0161083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985067/
https://www.ncbi.nlm.nih.gov/pubmed/27526095
http://dx.doi.org/10.1371/journal.pone.0161083

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