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p62/Sequestosome-1 Is Indispensable for Maturation and Stabilization of Mallory-Denk Bodies
Mallory-Denk bodies (MDBs) are hepatocytic protein aggregates found in steatohepatitis and several other chronic liver diseases as well as hepatocellular carcinoma. MDBs are mainly composed of phosphorylated keratins and stress protein p62/Sequestosome-1 (p62), which is a common component of cytopla...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985067/ https://www.ncbi.nlm.nih.gov/pubmed/27526095 http://dx.doi.org/10.1371/journal.pone.0161083 |