Comparative Single-Cell Analysis of Different E. coli Expression Systems during Microfluidic Cultivation

Recombinant protein production is mostly realized with large-scale cultivations and monitored at the level of the entire population. Detailed knowledge of cell-to-cell variations with respect to cellular growth and product formation is limited, even though phenotypic heterogeneity may distinctly ham...

Descripción completa

Detalles Bibliográficos
Autores principales: Binder, Dennis, Probst, Christopher, Grünberger, Alexander, Hilgers, Fabienne, Loeschcke, Anita, Jaeger, Karl-Erich, Kohlheyer, Dietrich, Drepper, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985164/
https://www.ncbi.nlm.nih.gov/pubmed/27525986
http://dx.doi.org/10.1371/journal.pone.0160711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985164/
https://www.ncbi.nlm.nih.gov/pubmed/27525986
http://dx.doi.org/10.1371/journal.pone.0160711

Ejemplares similares