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Comparative Single-Cell Analysis of Different E. coli Expression Systems during Microfluidic Cultivation
Recombinant protein production is mostly realized with large-scale cultivations and monitored at the level of the entire population. Detailed knowledge of cell-to-cell variations with respect to cellular growth and product formation is limited, even though phenotypic heterogeneity may distinctly ham...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985164/ https://www.ncbi.nlm.nih.gov/pubmed/27525986 http://dx.doi.org/10.1371/journal.pone.0160711 |