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Abelson kinase acts as a robust, multifunctional scaffold in regulating embryonic morphogenesis

Abelson family kinases (Abls) are key regulators of cell behavior and the cytoskeleton during development and in leukemia. Abl’s SH3, SH2, and tyrosine kinase domains are joined via a linker to an F-actin–binding domain (FABD). Research on Abl’s roles in cell culture led to several hypotheses for it...

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Detalles Bibliográficos
Autores principales: Rogers, Edward M., Spracklen, Andrew J., Bilancia, Colleen G., Sumigray, Kaelyn D., Allred, S. Colby, Nowotarski, Stephanie H., Schaefer, Kristina N., Ritchie, Benjamin J., Peifer, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985262/
https://www.ncbi.nlm.nih.gov/pubmed/27385341
http://dx.doi.org/10.1091/mbc.E16-05-0292